Polyethylene terephthalate (PET) is primarily used is packaging applications of food and beverages. It is used to package water, soft drinks, alcoholic beverages, and food among others. The demand for PET has been surging at a robust growth rate of more than 9%, with its estimated global annual demand of more than 50 million tons per year. However as polyethylene terephthalate is a downstream derivative of crude oil, the market is susceptible to the price volatility of crude oil. Moreover, the growing public consciousness coupled with environmental sustainability factors has led to the development of bio-based polyethylene terephthalate. Bio-based PET utilizes chemical intermediates which reduce the dependence on petroleum resources. Bio-based PET is at a nascent stage in the market, and is commercially available as partially bio-based product. Most of the bio-based PET available in the market is manufactured from bio-based ethylene glycol. However most of the market is still dominated by traditional PET, utilizing fossil fuel, while bio-based PET accounts for about 40% of the global bio plastics production capacity. The share of bio-based PET in bio plastics production is expected to rise astronomically in the foreseeable future.
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The major causes of dilated cardiomyopathy are genetics, birth defects, infections, drug and alcohol abuse, certain cancer medications and exposure to toxins like lead, mercury and cobalt. In case of dilated cardiomyopathy, male patients are more prone to it than female patients, ratio is approximately 3:1. According to American Stroke Association, dilated cardiomyopathy is the most common form of cardiomyopathy and accounts for approximately 55 to 60% of all childhood cardiomyopathies. According to the pediatric cardiomyopathy registry database, this form of myopathy is detected in roughly 1 to 2 per 200,000 children with roughly one new case per 160,000 children reported each year in the United States.
The companies involved in the dilated cardiomyopathy therapeutics clinical trials areAastrom Biosciences, Inc., t2cure GmbH, Zensun (Shanghai) Sci& Tech Co., Ltd., Kasiak Research Pvt. Ltd., MyoKardia, Inc. and Capricor Therapeutics, Inc.
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