Polyethylene
terephthalate (PET) is primarily used is packaging applications of food and
beverages. It is used to package water, soft drinks, alcoholic beverages, and
food among others. The demand for PET has been surging at a robust growth rate
of more than 9%, with its estimated global annual demand of more than 50
million tons per year. However as polyethylene terephthalate is a downstream
derivative of crude oil, the market is susceptible to the price volatility of
crude oil. Moreover, the growing public consciousness coupled with
environmental sustainability factors has led to the development of bio-based
polyethylene terephthalate. Bio-based PET utilizes chemical intermediates which
reduce the dependence on petroleum resources. Bio-based PET is at a nascent
stage in the market, and is commercially available as partially bio-based
product. Most of the bio-based PET available in the market is manufactured from
bio-based ethylene glycol. However most of the market is still dominated by
traditional PET, utilizing fossil fuel, while bio-based PET accounts for about
40% of the global bio plastics production capacity. The share of bio-based PET
in bio plastics production is expected to rise astronomically in the
foreseeable future.
The major causes of dilated cardiomyopathy are genetics, birth defects,
infections, drug and alcohol abuse, certain cancer medications and exposure to
toxins like lead, mercury and cobalt. In case of dilated cardiomyopathy, male
patients are more prone to it than female patients, ratio is approximately 3:1.
According to American Stroke Association, dilated cardiomyopathy is the most
common form of cardiomyopathy and accounts for approximately 55 to 60% of all
childhood cardiomyopathies. According to the pediatric cardiomyopathy registry
database, this form of myopathy is detected in roughly 1 to 2 per 200,000
children with roughly one new case per 160,000 children reported each year in
the United States.
The companies involved in the dilated cardiomyopathy therapeutics
clinical trials areAastrom Biosciences, Inc., t2cure GmbH, Zensun (Shanghai)
Sci& Tech Co., Ltd., Kasiak Research Pvt. Ltd., MyoKardia, Inc. and
Capricor Therapeutics, Inc.
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